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Chapter 2 looks at the story of the research

Chapter 2 looks at the story of the research

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AbstractFamiliarity can imply a reduction of fear and anxiety, which may render learning and memory performance insensitive to NMDA receptor antagonism. Our previous study indicates that MK 801 (dizocilpine), NMDA antagonist steriods, increased anxiety and prevented the acquisition of a spatial memory task. Here, we examined whether MK 801 will produce anxiety in mice that were familiar with the test environment.

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