We previously discovered several TRPC1/4/5 modulators steroids, including the xanthine based small molecule Pico145, a potent TRPC1/4/5 channel inhibitor that shows selectivity for heteromeric TRPC1:C4 channels over other TRPC1/4/5 channels. This will enable future development of small molecules that target specific TRPC4 or TRPC5 channels,...
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"Literally, all Governments around the world should be looking at [the reports] to see what are we saying," Sir Robert Watson, Chair of the Intergovernmental Science Policy Platform on Biodiversity and Ecosystem Services (IPBES) toldUN Newsahead of the body's sixth plenary session which will run...
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Some City officials believe that this will be of significant financial and exposure benefit. The fact is that if we did not break ground for a second sheet of ice by September of last year, BC Games would have pulled the games from Terrace and...
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Running an inventory of the cricket grounds across the globe I've been too, it was hard to rival the interactivity of the fans at the Premadasa. This wasn't up there in the pantheon of pre game rituals Liverpool fans singing their anthem in a match...