Regardless of whether you swim like a fish or a squirrel

26 dec Regardless of whether you swim like a fish or a squirrel

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steriods Their growth was significantly inhibited by gefitinib (p=0.039) over the study period while after only 2 weeks of gefitinib treatment tumours showed a decrease in the level of Ki67 staining (p = 0.068).Conclusion. Acquired tamoxifen resistance in vivo both in patients and in a xenograft model appears to be in part mediated through EGFR pathway signalling and this can be blocked and growth inhibited with gefitinib. In ER 4 negative tumours the effects of gefitinib were less striking, suggesting alternative signalling pathways are dominant in promoting their growth despite obvious overexpression of EGFR.. steriods

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